Bluffs, Blues, and the Mighty Mississippi
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Bluffs, Blues, and the Mighty Mississippi

Bluffs, Blues, and the Mighty Mississippi

Rock Island, IL 61201Memphis, TN 38103

4 days15 stops
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4
Days
15
Stops
active
Region

Rock Island, IL 61201Memphis, TN 38103

Embark on a journey down the Great River Road, tracing the Mississippi from the rolling bluffs of Iowa to the soulful heart of the Tennessee Delta. This trip blends American history, iconic music, and hearty river cuisine, showcasing the evolving landscape and culture along the nation's most storied waterway.

Trip highlights

Mississippi River Visitor Center
Mississippi River Visitor Center
Gateway Arch National Park
Gateway Arch National Park
Big River Crossing
Big River Crossing
Gus's World Famous Fried Chicken
Gus's World Famous Fried Chicken

The route

  1. 1Rock Island, IL 61201Start · 41.5448, -90.5843
  2. 2Mississippi River Visitor CenterStop · 41.5179, -90.5644
  3. 3Crane & Pelican CafeStop · 41.2829, -90.7225
  4. 4Mark Twain Boyhood Home & MuseumStop · 39.7123, -91.3581
  5. 5Garth Woodside MansionStop · 39.6475, -91.4081
  6. 6Mark Twain CaveStop · 39.6858, -91.4078
  7. 7Gateway Arch National ParkStop · 38.6255, -90.1883
  8. 8Pappy's SmokehouseStop · 38.6350, -90.2241
  9. 9The Last HotelStop · 38.6327, -90.2006
  10. 10Kaskaskia Bell State Historic SiteStop · 37.9216, -89.9147
  11. 11Lambert's CafeStop · 36.8879, -89.5464
  12. 12Big River CrossingStop · 35.1280, -90.0743
  13. 13The Peabody MemphisStop · 35.1426, -90.0518
  14. 14National Civil Rights Museum at the Lorraine MotelStop · 35.1347, -90.0576
  15. 15Sun StudioStop · 35.1391, -90.0377
  16. 16Gus's World Famous Fried ChickenStop · 35.1383, -90.0579
  17. 17Memphis, TN 38103End · 35.1436, -90.0573

Day 2

Mississippi River Visitor Center
Historical Site

Mississippi River Visitor Center

Start your journey at the Rock Island Arsenal, where this center offers panoramic views of the Mississippi River and Lock and Dam 15. Watch as barges and boats navigate the locks, and learn about the river's vital role in commerce and ecology from the U.S. Army Corps of Engineers.

Crane & Pelican Cafe
Dining

Crane & Pelican Cafe

Enjoy lunch in a historic 1851 river pilot's home with beautiful views of the river. This charming café serves creative sandwiches, salads, and entrees, offering a perfect taste of local hospitality in the town where the show 'American Pickers' began.

Mark Twain Boyhood Home & Museum
Historical Site

Mark Twain Boyhood Home & Museum

Step into the world of Samuel Clemens and his famous characters, Tom Sawyer and Huckleberry Finn. This collection of eight historic properties includes Twain's home, the J.M. Clemens Justice of the Peace office, and interactive exhibits that bring 19th-century river town life into focus.

Garth Woodside Mansion
Lodging

Garth Woodside Mansion

Stay overnight in a magnificent Second Empire Victorian mansion where Mark Twain was a frequent guest. This historic bed and breakfast offers elegant rooms, beautiful grounds, and a peaceful retreat just outside of downtown Hannibal.

Day 3

Mark Twain Cave
Outdoor Adventure

Mark Twain Cave

Explore the very cave that Mark Twain made famous in 'The Adventures of Tom Sawyer.' Take a guided tour through the labyrinthine passages of Missouri's oldest show cave and see the signatures left on the walls by visitors since 1819.

Gateway Arch National Park
Historical Site

Gateway Arch National Park

Witness the iconic 630-foot monument symbolizing the westward expansion of the United States. Take the tram ride to the top for breathtaking views of the city and the Mississippi River, and explore the excellent museum below detailing the story of St. Louis's role in American history.

Pappy's Smokehouse
Dining

Pappy's Smokehouse

Experience legendary St. Louis-style BBQ. Known for its slow-smoked Memphis-style ribs that are finished with a sweet, tangy glaze, Pappy's is a local institution that consistently ranks among the best barbecue joints in the country. Expect a line, but it's well worth the wait.

The Last Hotel
Lodging

The Last Hotel

Spend the night in a beautifully restored historic building that once housed the International Shoe Company. The hotel blends industrial chic with modern luxury and features a stunning lobby, a rooftop pool, and a unique, vibrant atmosphere in the heart of the city.

Day 4

Kaskaskia Bell State Historic Site
Historical Site

Kaskaskia Bell State Historic Site

Make a unique stop at the 'Illinois' Liberty Bell,' a gift from King Louis XV of France in 1741. This site is located on Kaskaskia Island, the only part of Illinois west of the Mississippi, accessible via a bridge from Missouri. It's a fascinating and often overlooked piece of regional history.

Lambert's Cafe
Dining

Lambert's Cafe

Experience the one-of-a-kind 'Home of Throwed Rolls.' This iconic restaurant is famous for its hearty Southern cooking and for servers who literally throw hot, fresh dinner rolls across the dining room to waiting customers. It's a fun, memorable, and delicious stop.

Big River Crossing
Scenic Viewpoint

Big River Crossing

Walk across the Mississippi River on the country's longest active rail/bicycle/pedestrian bridge. The nearly mile-long crossing offers incredible views of the Memphis skyline and the river itself, providing a dramatic entrance to the city as you literally cross the state line from Arkansas to Tennessee on foot.

The Peabody Memphis
Lodging

The Peabody Memphis

Stay at the legendary 'South's Grand Hotel,' famous for its opulent architecture and the twice-daily march of the Peabody Ducks through the lobby. This historic hotel is an attraction in itself and places you in the center of downtown Memphis.

Day 5

National Civil Rights Museum at the Lorraine Motel
Historical Site

National Civil Rights Museum at the Lorraine Motel

A profoundly moving and essential American experience, this museum is built around the former Lorraine Motel, where Dr. Martin Luther King Jr. was assassinated. The exhibits trace the history of the Civil Rights Movement from slavery to the present day.

Sun Studio
Culture Arts

Sun Studio

Visit the 'Birthplace of Rock 'n' Roll' where legends like Elvis Presley, B.B. King, Johnny Cash, and Jerry Lee Lewis made their first recordings. Take the guided tour to hear priceless outtakes, stand in the exact spot where Elvis first sang, and feel the history of a room that changed the world.

Gus's World Famous Fried Chicken
Dining

Gus's World Famous Fried Chicken

End your trip with a Memphis culinary institution. Gus's serves up spicy, crispy, and juicy fried chicken that has locals and tourists lining up. The recipe is a closely guarded family secret, delivering a perfect kick in a no-frills, authentic Southern atmosphere.

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Mississippi River Visitor Center

Mississippi River Visitor Center

Start your journey at the Rock Island Arsenal, where this center offers panoramic views of the Mississippi River and Lock and Dam 15. Watch as barges and boats navigate the locks, and learn about the river's vital role in commerce and ecology from the U.S. Army Corps of Engineers.

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Mississippi River